1H-Indole-3-carboxylic acid, 5-nitro-

1H-Indole-3-carboxylic acid, 5-nitro- - Names and Identifiers

Name	5-Nitroindole-3-carboxylic acid
Synonyms	RARECHEM AL BE 1168 5-NITROINDOLE-3-CARBOXYLIC ACID 5-Nitroindole-3-carboxylic acid Indole-3-carboxylicacid, 5-nitro- 5-nitro-1H-indole-3-carboxylic acid 5-Nitro-1H-indole-3-carboxylic acid 1H-Indole-3-carboxylicacid, 5-nitro- 1H-Indole-3-carboxylic acid, 5-nitro- 2-amino-4-(6-nitro-1,3-benzodioxol-5-yl)-6-(3-nitrophenyl)pyridine-3-carbonitrile
CAS	6958-37-8
InChI	InChI=1S/C9H6N2O4/c12-9(13)7-4-10-8-2-1-5(11(14)15)3-6(7)8/h1-4,10H,(H,12,13)

1H-Indole-3-carboxylic acid, 5-nitro- - Physico-chemical Properties

Molecular Formula	C9H6N2O4
Molar Mass	206.15
Density	1.632±0.06 g/cm3(Predicted)
Melting Point	276-278 °C (decomp)
Boling Point	520.8±30.0 °C(Predicted)
Flash Point	268.8 °C
pKa	3.38±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

1H-Indole-3-carboxylic acid, 5-nitro- - Introduction

Acid is an organic compound with the chemical formula C9H6N2O4. It is a yellow crystalline solid with an aromatic odor similar to indole. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Yellow crystalline solid
-Melting point: 200-203°C
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethylformamide
- pH: Neutral

Use:
Acid has important applications in chemical research. It is commonly used as a fluorescent probe, luminescent materials and heterocyclic compounds synthesis intermediates. In addition, it may also have anti-inflammatory, antioxidant and anti-tumor biological activity.

Preparation Method:
It can be prepared by reacting indole-3-carboxylic acid with nitric acid in the presence of nitrogen and sodium nitrite. This reaction is usually carried out under acidic conditions, for example using sulfuric acid as a catalyst. After completion of the reaction, the product can be obtained by crystallization and filtrate treatment.

Safety Information:
No clear toxicity data has been reported for acid. However, as an organic compound, in general, appropriate handling measures should be in place to avoid contact with the skin, inhalation or ingestion. Appropriate work clothes, protective gloves and eye protection are recommended for use. Follow good laboratory practices and pay attention to how chemicals are stored and handled.

Last Update：2024-04-10 22:29:15